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Vol 4 No 1 (2017): Leucocyte, Neutrophils counts and Procalcitonin levels in Salmonella and Gram-negative Bacteremias

Suhendro Suwarto1, Zahra Farhanni Suhardi2, Amin Soebandrio3,4
1Division of Tropical and Infectious Diseases, Department of Internal Medicine, Faculty of Medicine Universitas Indonesia, Dr. Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia.
2 Faculty of Medicine Universitas Indonesia.
3Eijkman Institute for Molecular Biology, Jakarta, Indonesia.
4Department of Microbiology, Faculty of Medicine Universitas Indonesia.


Background: The laboratory marker of leucocytes, neutrophils and procalcitonin (PCT) are elevated in Gram-negative-infected patients. Salmonella species, a cause of typhoid fever, are also a type of Gram-negative bacteria. We investigated the laboratory marker of bacterial infection levels in Salmonella and Gram-negative bacteremias.
Methods: This retrospective study was conducted in Jakarta, Indonesia. Sixty-one patients with positive blood cultures of Salmonellaor Gram-negative bacteria who were admitted to the hospital from April 2014 through May 2017 were included. Twenty-seven patients (44,3%) had Salmonella, and 34 patients (55,7%) had Gram-negative bacteremias. The following laboratory parameters were recorded: leucocyte count, neutrophil count, and PCT levels. Bivariate analysis was used to analyze the differences in the laboratory marker between Salmonella and Gram-negative bacteremias.
Results: Gram-negative bacteremia was significantly associated with an elevated leucocyte count (p<0.001), neutrophil count (p<0,001) and PCT levels (p<0,001). The leucocyte count cut-off of ≥10.5x103/μL, a neutrophil countcut-off of ≥80,9% and a PCT level cut-off of ≥1,18 ng/ml were significantly higher in the Gram-negative bacteremia group compared with the Salmonella group (p<0,001 for each variable).
Conclusion: Leucocyte, neutrophil counts, and PCT levels in Gram-negative bacteremia were higher than inSalmonella bacteremia.
Keywords: Gram negative bacteremia,leucocyte, neutrophils cells counts, procalcitonin, Salmonella bacteremia.

Published: 2018-01-13
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Jurnal Chest Vol. 1 No. 2    April - June  2014

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Jurnal Chest Vol. 2 No. 2        April - June 2015

Jurnal Chest Vol. 2 No. 3        July - September 2015

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Jurnal Chest Vol. 4 No. 1       January - March 2017


Table of Contents

Extrapulmonary Tuberculosis-a Diagnosis Challenge .......................... TellyKamelia, Nice Fenobileri   Read More

Original Article

Pelacakan Pasien TB MDR Terkonfirmasi Yang Belum Memulai Pengobatan Di RSUP Dr. Hasan Sadikin Bandung Periode April 2012 – Februari 2015.....Dedi Suyanto, Basti Andriyoko, Ii Sariningsih


Echocardiographic Epicardial Adipose Tissue Thickness As A Predictor Of Severe Coronary Artery Disease In Indonesia...........Mirnawati Mappiare, Abdul Hakim Alkatiri, Peter Kabo


Leucocyte, Neutrophils counts and Procalcitonin levels in Salmonellaand Gram-negative Bacteremias .............. Suhendro Suwarto, Zahra Farhanni Suhardi, Amin Soebandrio


Case Report

Management of Acute Heart Failure Post ST-Segment Elevation Myocardial Infarction in Non-Revascularization Capable Hospital: A Case Report..........Ivana Purnama Dewi, Kristin Purnama Dewi, Rizaldy Pinzon, Bagus Andi Pramono


Acute Postpartum Pulmonary Edema in a 34-year-old Preeclampsia Woman:Case Report................ Yohanes Susanto, Patrice Ginting, Ruddy Hardiansyah


Efektivitas Kortikosteroid sebagai Terapi Adjuvan pada Pneumonia Komunitas Berat: Laporan Kasus Berbasis Bukti........Michelle Audrey Darmadi, Gurmeet Singh



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